Fatty acid esters
Medchemexpress LLC Monomethyl auristatin E | 474645-27-7 | C39H67N5O7 | 50 MG
Monomethyl auristatin E (MMAE) is a potent tubulin polymerization inhibitor. This product is produced following GMP guidelines and is intended for research use only. It has demonstrated significant biological activity in various cancer models, including its ability to enhance the effects of radiation therapy.
- Functions as a tubulin polymerization inhibitor.
- Effectively released within CD30+ cancer cells.
- Exerts cytotoxic activity on bystander cells.
- Sensitizes colorectal and pancreatic cancer cells to ionizing radiation.
- Correlates with mitotic arrest.
- Leads to tumor growth delay in vivo when combined with radiation.
Medchemexpress LLC Monoethyl pimelate | 33018-91-6 | MFCD00014383 | >98.0% | 188.22 g/mol | C9H16O4 | 100 G
Monoethyl pimelate is the monoethyl ester of pimelic acid used as a chemical building block and PROTAC linker for small-molecule degrader synthesis. It serves as a synthetic intermediate in esterification and linker-construction chemistry and is supplied with product documentation for research use.
- Monoethyl ester of pimelic acid.
- Function as a PROTAC linker and synthetic intermediate.
- Reported molecular formula C9H16O4 and molecular weight 188.22 g/mol.
- Documentation includes a product data sheet, SDS, and handling instructions.
- Available in multiple package sizes, including 100 g.
Cayman Chemical Lauric Acid Fatty Acids and De
A medium-chain fatty acid; has been found at high levels in coconut oil; induces the activation of NF-κB and the expression of COX-2, iNOS, and IL-1α in RAW 264.7 cells at 25 µM
Cayman Chemical Lauric Acid Leelamide
Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits PDHK with an IC50 value of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of PLA2 activity from a variety of sources.{14107} There are no published studies of the pharmacological properties of lauric acid leelamide.
Medchemexpress LLC Octanoyl-L-carnitine-d3 chloride | 1334532-24-9 | MFCD22419179 | 99.9% | 326.87 g/mol | C15H27D3ClNO4 | 5 MG
Octanoyl-L-carnitine-d3 chloride is the deuterium-labeled chloride salt of octanoyl-L-carnitine supplied as a solid stable-isotope standard for analytical and research use. It is intended as an internal standard for LC-MS/MS and GC-MS assays and for metabolic tracing studies of fatty acid and carnitine metabolism. The product is provided in small milligram packs suitable for reference standards and method development.
- Deuterium-labeled internal standard for mass spectrometry assays.
- Provided as the chloride salt for compatibility with aqueous and organic solvents.
- High purity suitable for quantitative analysis.
- Solid, white to off-white appearance for easy handling and storage.
- Supplied in small milligram quantities for reference standard use.
- Useful for metabolic tracing and quantification of acylcarnitines.
Medchemexpress LLC Monomethyl auristatin E | 474645-27-7 | MFCD00868128 | C39H67N5O7 | 50 MG
Monomethyl auristatin E (MMAE) (Standard) is an analytical standard for research and analytical applications. This synthetic derivative of dolastatin 10 acts as a potent mitotic inhibitor by inhibiting tubulin polymerization and is widely used as a cytotoxic component in antibody-drug conjugates (ADCs) for various cancer types. This analytical standard is suitable for qualitative, quantitative, and methodological research experiments.
- Analytical standard grade
- Functions as a potent mitotic inhibitor
- Inhibits tubulin polymerization
- Utilized as a cytotoxic component in antibody-drug conjugates
- Purity of 99.99%
- Appears as a white to off-white solid
- Commonly employed in HPLC, GC, and MS techniques
Medchemexpress LLC Hexadecyl palmitate | 540-10-3 | 98.1% | 480.86 | 25 G
Hexadecyl palmitate is an organic compound and analytical standard used in research and analytical applications. It functions as an emollient, thickener, and skin conditioning agent, primarily in the cosmetic industry for products like moisturizers, lotions, and creams to enhance texture and smooth application. Its applications extend to pharmaceuticals, food additives, and lubricants.
- Functions as an emollient, thickener, and skin conditioning agent
- Used in skin care products to improve texture and aid smooth application
- Applicable in pharmaceuticals, food additives, and lubricants
- Intended for research and analytical applications
Cayman Chemical Cholesteryl Behenate 100mg
A cholesterol ester; has been used as an internal standard for the quantification of cholesterol esters in human meibum samples
Selleck Chemical LLC Ribociclib succinate S5188-5mg
Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Cayman Chemical 3hydroxy LaurIc ACD mthyl 10mg
A hydroxy fatty acid methyl ester; has been found in PHA polymers produced by P. putida and D. tsuruhatensis
![Medchemexpress LLC 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole | 875787-07-8 | MFCD16495812 | 100.0% | 422.78 g·mol⁻¹ | C21H12ClF5N2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244381.png-250.jpg)
Medchemexpress LLC 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole | 875787-07-8 | MFCD16495812 | 100.0% | 422.78 g·mol⁻¹ | C21H12ClF5N2 | 50 MG
LXR-623 is a brain-penetrant small-molecule agonist of liver X receptors with potent activity at both LXRα and LXRβ. It is used in preclinical research to modulate cholesterol homeostasis and has demonstrated activity in glioblastoma models. The compound is supplied as a high-purity solid with recommended solvents and storage conditions for in vitro and in vivo studies.
- Brain-penetrant LXRα/β agonist with LXRα IC50 = 24 nM and LXRβ IC50 = 179 nM.
- Molecular formula C21H12ClF5N2 and molecular weight 422.78 g·mol⁻¹.
- High purity (99.95%) suitable for research applications.
- Soluble in DMSO at ≥ 47 mg/mL and formulatable for in vivo dosing at ≥ 2.5 mg/mL in common vehicles.
- Stable as a powder at -20 °C for up to 3 years; store in solvent at -80 °C for long-term storage.
- Available in multiple solid pack sizes, including 50 mg, for laboratory use.